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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCYT1A
All Species:
31.52
Human Site:
S282
Identified Species:
49.52
UniProt:
P49585
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49585
NP_005008.2
367
41731
S282
I
Q
K
W
E
E
K
S
R
E
F
I
G
S
F
Chimpanzee
Pan troglodytes
XP_001143741
320
37092
R248
R
S
K
E
F
V
N
R
V
E
E
K
S
H
D
Rhesus Macaque
Macaca mulatta
XP_001090055
338
38695
R266
R
S
K
E
F
V
N
R
V
E
E
K
S
H
D
Dog
Lupus familis
XP_535776
367
41764
S282
I
Q
K
W
E
E
K
S
R
E
F
I
G
S
F
Cat
Felis silvestris
Mouse
Mus musculus
P49586
367
41648
S282
I
Q
K
W
E
E
K
S
R
E
F
I
G
S
F
Rat
Rattus norvegicus
P19836
367
41662
S282
I
Q
K
W
E
E
K
S
R
E
F
I
G
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517894
294
33692
G221
G
N
F
L
E
M
F
G
P
E
G
A
L
K
H
Chicken
Gallus gallus
XP_422725
367
42078
S282
I
Q
K
W
E
E
K
S
R
E
F
I
G
N
F
Frog
Xenopus laevis
NP_001089299
367
41920
S282
I
Q
K
W
E
E
K
S
R
E
F
I
G
N
F
Zebra Danio
Brachydanio rerio
NP_001018571
359
41135
S279
I
Q
K
W
E
E
K
S
R
E
F
I
G
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647621
526
58183
F412
I
D
T
F
L
L
L
F
G
R
E
N
L
N
H
Honey Bee
Apis mellifera
XP_395764
403
46370
F323
I
D
A
F
L
L
L
F
G
R
E
G
R
L
S
Nematode Worm
Caenorhab. elegans
P49583
362
41751
G284
D
T
F
H
K
D
G
G
L
N
A
F
G
G
R
Sea Urchin
Strong. purpuratus
XP_001180754
425
48260
S298
L
Q
K
W
E
E
K
S
R
E
M
I
G
N
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13259
424
49388
Q325
N
E
L
K
K
Q
N
Q
R
Q
R
K
Q
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.5
60.7
96.4
N.A.
96.1
96.4
N.A.
77.3
89
86.3
76.2
N.A.
36.1
46.4
37.8
45.4
Protein Similarity:
100
69.2
71.6
98
N.A.
97.5
97.2
N.A.
78.1
95
91.2
84.1
N.A.
46
62
52.3
60
P-Site Identity:
100
13.3
13.3
100
N.A.
100
100
N.A.
13.3
93.3
93.3
93.3
N.A.
6.6
6.6
6.6
80
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
20
13.3
20
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
0
0
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
14
0
0
0
7
0
0
0
0
0
0
0
0
14
% D
% Glu:
0
7
0
14
60
54
0
0
0
74
27
0
0
0
0
% E
% Phe:
0
0
14
14
14
0
7
14
0
0
47
7
0
0
60
% F
% Gly:
7
0
0
0
0
0
7
14
14
0
7
7
60
7
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
14
14
% H
% Ile:
60
0
0
0
0
0
0
0
0
0
0
54
0
0
0
% I
% Lys:
0
0
67
7
14
0
54
0
0
0
0
20
0
7
0
% K
% Leu:
7
0
7
7
14
14
14
0
7
0
0
0
14
7
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% M
% Asn:
7
7
0
0
0
0
20
0
0
7
0
7
0
40
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
54
0
0
0
7
0
7
0
7
0
0
7
0
0
% Q
% Arg:
14
0
0
0
0
0
0
14
60
14
7
0
7
0
7
% R
% Ser:
0
14
0
0
0
0
0
54
0
0
0
0
14
27
7
% S
% Thr:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
14
0
0
14
0
0
0
0
0
0
% V
% Trp:
0
0
0
54
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _